StochStack

prototype 17

CTM 每日控制面板

给 CTM 的统一运营驾驶舱：融合 CTMS/EDC/RTSM/Excel 信号，检测指标偏移，并通过 SOP as code + ReAct 路由给出行动方案。

Oncology · NSCLC · Phase III · GlobalSOP Registry 1.1.0 (yaml)updated: 2026-03-01

数据源健康度

CTMS

正常

Milestones / Site startup / Budget

last sync: 3/1/2026, 7:20:00 AM

EDC

滞后

Enrollment / Query burden / Protocol deviations

last sync: 2/28/2026, 10:15:00 PM

RTSM

正常

Randomization / Drug supply

last sync: 3/1/2026, 6:55:00 AM

Excel Upload

预警

Regional FTE snapshots

last sync: 2/27/2026, 4:10:00 PM

KPI 偏移看板

Site Startup

高风险

计划值: 42 Activated Sites · 实际值: 36 Activated Sites

偏移: -14.3% · Owner: Global Site Ops

Patient Recruitment

高风险

计划值: 480 Randomized Patients · 实际值: 401 Randomized Patients

偏移: -16.5% · Owner: Country CTM

Budget Consumption

高风险

计划值: 58 % Burn · 实际值: 65 % Burn

偏移: +12.1% · Owner: Trial Finance

FTE Utilization

高风险

计划值: 74 % Utilization · 实际值: 87 % Utilization

偏移: +17.6% · Owner: Resource Manager

Mitigation 方案

Site Startup (-14.3%)

Owner: Global Site Ops

SOP.SKILL.SITE_STARTUP_RECOVERY

  • - Check startup bottleneck by country and ethics package status.
  • - Trigger accelerated document cycle with local startup vendor.

Patient Recruitment (-16.5%)

Owner: Country CTM

SOP.SKILL.RECRUITMENT_RECOVERY

  • - Segment low-performing sites by screen-failure and consent rate.
  • - Launch targeted patient-finding channel playbook per country.

Budget Consumption (+12.1%)

Owner: Trial Finance

SOP.SKILL.BUDGET_GUARDRAIL

  • - Run variance analysis by vendor, region, and activity bucket.
  • - Freeze non-critical discretionary spend for current cycle.

FTE Utilization (+17.6%)

Owner: Resource Manager

SOP.SKILL.FTE_REALLOCATION

  • - Map role-level workload against current sprint deliverables.
  • - Reassign support roles from low-risk to high-risk workstreams.

今日行动队列

  1. task 1

    Site Startup mitigation standup

    owner: Global Site Ops · skill: SOP.SKILL.SITE_STARTUP_RECOVERY

  2. task 2

    Patient Recruitment mitigation standup

    owner: Country CTM · skill: SOP.SKILL.RECRUITMENT_RECOVERY

  3. task 3

    Budget Consumption mitigation standup

    owner: Trial Finance · skill: SOP.SKILL.BUDGET_GUARDRAIL

  4. task 4

    FTE Utilization mitigation standup

    owner: Resource Manager · skill: SOP.SKILL.FTE_REALLOCATION

ReAct Skill 路由

意图匹配

SOP.SKILL.RECRUITMENT_RECOVERY

v1.3.0 · active · effective 2026-02-22

reviewer: Clinical Quality Review Board · approved by: VP Clinical Development (2026-02-23)

score: 1

Stabilize enrollment trajectory and reduce milestone slippage risk.

推理轨迹

  • - Detected intent keywords: enrollment
  • - Matched SOP header: SOP.SKILL.RECRUITMENT_RECOVERY
  • - Cross-check current KPI drift and source freshness before action.
  • - Execute SOP steps and produce auditable outputs for CTM governance.

执行动作

  • - Segment low-performing sites by screen-failure and consent rate.
  • - Launch targeted patient-finding channel playbook per country.
  • - Reallocate recruitment support FTE to top opportunity sites.

预期输出

Recovery plan memo · Country recruitment actions · Milestone risk note

latest change: v1.3.0 (2026-02-22) by Patient Strategy Office

update log

Prototype Change Log

  1. 2026-03-01 · v0.3.0

    审批流字段 + 仅加载 active 生效策略

    • - SOP skill registry schema 新增 reviewer/approvedBy/approvalDate 审批字段。
    • - Registry loader 调整为只激活“已审批且 active”的 skill。
    • - CTM dashboard 在路由结果中展示 SOP 审批元信息。

  2. 2026-03-01 · v0.2.0

    可配置 SOP Skill 注册表（YAML/JSON）

    • - 新增版本化 SOP registry 读取器：优先 YAML，回退 JSON。
    • - Skill 定义升级为带 sopVersion/status/effectiveDate/owners/changeLog 的配置结构。
    • - 界面新增 registry 版本、来源格式与最新变更元信息展示。

  3. 2026-03-01 · v0.1.0

    CTM 每日控制面板基线版本

    • - 新增 CTMS/EDC/RTSM/Excel 多源健康看板。
    • - 实现 site startup、recruitment、budget burn、FTE utilization 四类指标偏移检测。
    • - 新增与 SOP skill header 绑定的 mitigation 方案与每日行动队列。
    • - 新增 ReAct 风格意图路由，展示 reasoning/action 轨迹。