Select Protocol
Phase 3 First-line NSCLC Combination Therapy
Randomized Phase 3 trial comparing SOC vs investigational combo in first-line metastatic NSCLC.
prototype 04
Protocol Q&A & Logic Engine
Select a protocol by therapeutic area, ask structured questions, and run patient eligibility / medication restriction / lab manual checks with evidence trace.
Upload Protocol PDF -> Auto Structured JSON
Upload a protocol PDF. The engine uses Qwen to extract structured schema and inject it into the current protocol selector.
Recommended Questions
Eligibility Check
Medication Restriction Check
Lab Manual Storage Check
No specific match found; showing protocol-level guidance.
Knowledge Graph Structure
Patient Profile
I/E Criteria
Medication Rules
Schedule of Activities
Lab Manual
patient -> ie: eligibility check
patient -> med: restriction check
ie -> soa: on-study workflow
soa -> lab: sample handling
Inclusion Criteria
- - I1: Age 18-75 years
- - I2: Histologically confirmed stage IV NSCLC
- - I3: ECOG performance status 0-1
- - I4: ANC >= 1.5 x10^9/L, Platelets >= 100 x10^9/L
- - I5: ALT/AST <= 2.5 x ULN (<=5 x ULN if liver metastases)
- - I6: Creatinine clearance >= 50 mL/min
Exclusion Criteria
- - E1: Untreated or symptomatic CNS metastases
- - E2: Active uncontrolled infection
- - E3: Pregnancy or breastfeeding
- - E4: Prior anti-PD-1/PD-L1 treatment in metastatic setting
update log
Prototype Change Log
2026-03-01 · v0.4.0
PDF Upload and Auto-Structured Extraction
- - Added protocol PDF upload and Qwen-based extraction endpoint.
- - Injected extracted protocol JSON directly into engine selector.
- - Extended eligibility, med-check, and lab-manual evidence tracing.